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Adult T-cell leukemia/lymphoma (ATL) is a distinct neoplasia of peripheral T-lymphocytes caused by human T-cell lymphotropic virus type 1 (HTLV-1). HTLV-1 was discovered in after being isolated from cells derived from a cutaneous lymphoma, probably a mycosis fungoides (MF) lesion. Dec 16, - Adult T-cell leukemia/lymphoma (ATL) is defined as a histologically or cytologically proven peripheral T-cell malignancy associated with a.